OCD is an abbreviation that stands for Obsessive–compulsive disorder, a mental disorder.

OCD may also refer to:

• Obsessive–compulsive personality disorder (OCPD), a mental disorder that is often mistakenly called OCD
• On-call duty, a long shift that may be assigned to medical residents
• Ortho-Clinical Diagnostics, an American company
• Osteochondritis dissecans, a painful joint condition in humans and other animals

• OCD, the file suffix used by OCAD mapping software
• Object collision detection
• On-chip debugging
• OpenOCD (Open On-Chip Debugger), a debugger mostly used in embedded software development.

• Office of Civil Defense, the National Emergency Management Agency of the Philippines
• Office of Civilian Defense, a World War II–era U.S. government agency
• Office of Community Development, a part of the U.S. Department of Agriculture's rural development activities
• Office of Cultural Development, a part of the Louisiana Department of Culture, Recreation and Tourism

• OCD, the acronym for the Order of Discalced Carmelites (from the Latin, Ordo Carmelitarum Discalceatorum)

• "O.C.D.", a song by Suicide Silence from their third album The Black Crown
• Obsessive Completion Distinction, an achievement demanding extraordinary attention to detail in the video game World of Goo
• Octavian County Day School, a school attended by characters of Lisi Harrison's The Clique books
• OCD overdrive pedal by Fulltone
• "OCD", a song by Fitz and the Tantrums from All the Feels, 2019
• "OCD", a song by Logic featuring Dwn2Earth
• "OCD", a song by the Godfathers from Alpha Beta Gamma Delta, 2022
• A 1999 cassette album by the noise musician Prurient
• Offshore Development Center
• Okanogan Conservation District
• Oxford Classical Dictionary