Nunzio may refer to:

• A masculine Italian name.
• James Maritato (born 1972), who has used it as his ring name.

Other people with the name include:

• Gregory Corso, AKA Gregory Nunzio Corso (1930–2001), a Beat poet
• Nunzio DeFilippis, American writer of comic books and television
• Nick Discepola (born 1949), Italian-born Canadian politician whose given name is Nunzio
• Nunzio Ferraiuoli (1661–1735), Italian painter of the Baroque period
• Nunzio Gallo (1928–2008), Italian singer and actor
• Joseph Nunzio Latino (1937–2021), Roman Catholic Bishop of Jackson (Mississippi, US, 2003–2013)
• Nunzio Provenzano (1923–1997), Genovese crime family soldier

• Nunzio, a character in the Myth Adventures series created by Robert Asprin
• Sacred Silence, an Italian film originally titled Pianese Nunzio, 14 anni a maggio
• Nunzio (film), a 1978 American film starring David Proval