MBE may refer to:

• Master of Bioprocess Engineering
• Master of Bioethics
• Master of Bioscience Enterprise
• Master of Business Engineering
• Master of Business Economics

• The Mid-Brunhes Event, a climatic change at around 430,000 years ago
• Mode-based Execution Control, an x86 virtualization technology
• Model-based enterprise, a manufacturing strategy where a 3D model of a product is used to guide its life cycle
• Molecular-beam epitaxy, a thin-film crystal growth technique
• Molecular Biology and Evolution, a journal
• Multi-band excitation, a series of speech coding standards
• Multibeam echosounder, a device used to map ocean floors

• Member of the Most Excellent Order of the British Empire

• Mail Boxes Etc., a global chain of retail business service centers
• Management by exception, a style of business management
• Minority business enterprise, a classification of business
• Morning Becomes Eclectic, a radio program
• Multistate Bar Examination, an exam administered to most prospective American lawyers
• Monbetsu Airport's IATA code

• Mbe (disambiguation)