The Little Seven Conference was a high school athletic conference with its membership concentrated in southeastern Wisconsin. Competing from 1926 to 1934, its members belonged to the Wisconsin Interscholastic Athletic Association.

The Little Seven Conference, known as the Little Five Conference during its first season, was formed by five small high schools on the periphery of metropolitan Milwaukee in 1926: Hartland, Menomonee Falls, North Milwaukee, Oconomowoc and Pewaukee.^[1] Cedarburg and Port Washington joined after the first season, which is when the conference assumed the Little Seven name.^[2] In 1928, Norris Foundation became the eighth school to join the conference, but the Little Seven name remained in place despite the conference's expansion.^[3] In 1929, the village of North Milwaukee was annexed into the city of Milwaukee^[4][5] along with the high school, which joined the Milwaukee Public Schools district. Out of a desire to avoid confusion between North Milwaukee High School and the nearby North Division High School, North Milwaukee was renamed Custer High School after the original street it resided on.^[6] In 1930, the Little Seven lost four schools: Custer to the Milwaukee City Conference,^[7] Hartland to the Little Six Conference, Oconomowoc to the Little Ten Conference^[8] and Port Washington to compete independent of conference affiliation. Norris Foundation would leave to join the Southeastern Wisconsin Conference in 1932,^[9] and the three remaining schools competed informally for two more years^[10] before joining with Juneau High School in Dodge County to form the 4-C Conference.^[11]