Kurzrock–Miller test
The Kurzrock–Miller test is an in-vitro test of sperm–mucus interaction. It consists of establishing an interface between cervical mucus and liquefied semen.[1] It is one of the tests used for investigating infertility.
Etymology
The test is named after Raphael Kurzrock and Thomas Grier Miller.[2]
Interpretation
- Negative test: Spermatozoa congregate on semen side of the interface, but do not penetrate it.
- Abnormal: Spermatozoa penetrate the mucus, but rapidly become immobile or acquire shaking movement.
- Poor: after penetration, spermatozoa do not progress farther than 500 μm.
- Normal: Spermatozoa penetrate the mucus and >90% are motile with definite progression, crossing 3 cm at 30 minutes.[3]