Protein-coding gene in the species Homo sapiens
Kruppel-like factor 7 (ubiquitous) , also known as KLF7 , is a protein which in humans is encoded by the KLF7 gene .[ 5] [ 6]
This protein is a member of the Kruppel-like family of transcription factors .[ 7]
References
^ a b c GRCh38: Ensembl release 89: ENSG00000118263 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000025959 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Entrez Gene: KLF7 Kruppel-like factor 7 (ubiquitous)" .^ Matsumoto N, Laub F, Aldabe R, Zhang W, Ramirez F, Yoshida T, Terada M (October 1998). "Cloning the cDNA for a new human zinc finger protein defines a group of closely related Krüppel-like transcription factors" . The Journal of Biological Chemistry . 273 (43): 28229–37. doi :10.1074/jbc.273.43.28229 PMID 9774444 . ^ Bieker JJ (September 2001). "Krüppel-like factors: three fingers in many pies" . The Journal of Biological Chemistry . 276 (37): 34355–8. doi :10.1074/jbc.R100043200 PMID 11443140 .
Further reading
Cho SY, Park PJ, Shin HJ, et al. (2007). "(-)-Catechin suppresses expression of Kruppel-like factor 7 and increases expression and secretion of adiponectin protein in 3T3-L1 cells". Am. J. Physiol. Endocrinol. Metab . 292 (4): E1166–72. doi :10.1152/ajpendo.00436.2006 . PMID 17164435 . Kawamura Y, Tanaka Y, Kawamori R, Maeda S (2006). "Overexpression of Kruppel-like factor 7 regulates adipocytokine gene expressions in human adipocytes and inhibits glucose-induced insulin secretion in pancreatic beta-cell line" . Mol. Endocrinol . 20 (4): 844–56. doi :10.1210/me.2005-0138 PMID 16339272 . Kanazawa A, Kawamura Y, Sekine A, et al. (2005). "Single nucleotide polymorphisms in the gene encoding Krüppel-like factor 7 are associated with type 2 diabetes" . Diabetologia . 48 (7): 1315–22. doi :10.1007/s00125-005-1797-0 PMID 15937668 . Smaldone S, Laub F, Else C, et al. (2004). "Identification of MoKA, a novel F-box protein that modulates Krüppel-like transcription factor 7 activity" . Mol. Cell. Biol . 24 (3): 1058–69. doi :10.1128/MCB.24.3.1058-1069.2004 . PMC 321422 PMID 14729953 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 PMID 14702039 . Suzuki S, Chuang LF, Doi RH, Chuang RY (2004). "Identification of opioid-regulated genes in human lymphocytic cells by differential display: upregulation of Krüppel-like factor 7 by morphine". Exp. Cell Res . 291 (2): 340–51. doi :10.1016/S0014-4827(03)00408-7 . PMID 14644156 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Matsumoto N, Laub F, Aldabe R, et al. (1998). "Cloning the cDNA for a new human zinc finger protein defines a group of closely related Krüppel-like transcription factors" . J. Biol. Chem . 273 (43): 28229–37. doi :10.1074/jbc.273.43.28229 PMID 9774444 .
External links
(1) Basic domains
(1.1) Basic leucine zipper (bZIP )(1.2) Basic helix-loop-helix (bHLH )
Group A Group B Group CPAS Group D Group E Group F
(1.3) bHLH-ZIP (1.4) NF-1 (1.5) RF-X (1.6) Basic helix-span-helix (bHSH)
(2) Zinc finger DNA-binding domains
(2.1) Nuclear receptor (Cys4 )
subfamily 1 subfamily 2 subfamily 3 subfamily 4 subfamily 5 subfamily 6 subfamily 0
(2.2) Other Cys4 (2.3) Cys2 His2 (2.4) Cys6 (2.5) Alternating composition (2.6) WRKY
(4) β-Scaffold factors with minor groove contacts
(0) Other transcription factors
