John Rowe may refer to:

• John Rowe (Exelon), head of Chicago energy concern Exelon Corporation
• John Rowe (Aetna) (born 1944), former CEO and executive chairman of U.S. health care benefits company Aetna

• John Rowe (minister) (1626–1677), English clergyman
• John Rowe (actor) (born 1941), British actor
• John Rowe (naval officer), navy officer of the U.S. Navy during the First Barbary War
• John Rowe (merchant) (1715–1787), merchant and politician in Boston, Massachusetts, during the American Revolution
• John Rowe (author) (1936–2017), Australian author
• John Howland Rowe (1918–2004), American anthropologist
• John Rowe (Australian politician) (1816–1886), member of South Australian parliament
• John Carlos Rowe, American academic and author
• Jack Rowe (1856–1911), American baseball player for the Buffalo Bisons
• John Tetley Rowe (1861–1915), Anglican priest

• John Row (disambiguation)
• John Roe (disambiguation)
• Jonathan Rowe (disambiguation)