High Falls or Highfalls may refer to:

• The High Falls of the Baptism River in Tettegouche State Park, Minnesota
• The High Falls of the Pigeon River in Grand Portage State Park, Minnesota

• High Falls (Rochester, New York), a waterfall on the Genesee River in Rochester
• High Falls, New York, a hamlet
• High Falls Brewing Company, the former name of Genesee Brewing Company, a brewery in Rochester
• High Falls on the Oswegatchie River, a waterfall on the Oswegatchie River

• Highfalls, Alabama, an unincorporated community
• High Falls State Park in Georgia
• High Falls (DuPont State Forest), a waterfall on the Little River in North Carolina

• High Falls, Ontario, a ghost town near Walden