Protein-coding gene in the species Homo sapiens
General transcription factor 3C polypeptide 1 is a protein that in humans is encoded by the GTF3C1 gene .[ 5] [ 6] [ 7]
Interactions GTF3C1 has been shown to interact with GTF3C4 .[ 8]
References
^ a b c GRCh38: Ensembl release 89: ENSG00000077235 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032777 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Lagna G, Kovelman R, Sukegawa J, Roeder RG (May 1994). "Cloning and characterization of an evolutionarily divergent DNA-binding subunit of mammalian TFIIIC" . Mol. Cell. Biol . 14 (5): 3053–64. doi :10.1128/mcb.14.5.3053 . PMC 358673 PMID 8164661 . ^ L'Etoile ND, Fahnestock ML, Shen Y, Aebersold R, Berk AJ (Apr 1994). "Human transcription factor IIIC box B binding subunit" . Proc. Natl. Acad. Sci. U.S.A . 91 (5): 1652–6. Bibcode :1994PNAS...91.1652L . doi :10.1073/pnas.91.5.1652 PMC 43221 PMID 8127861 . ^ "Entrez Gene: GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa" .^ Hsieh YJ, Kundu TK, Wang Z, Kovelman R, Roeder RG (Nov 1999). "The TFIIIC90 subunit of TFIIIC interacts with multiple components of the RNA polymerase III machinery and contains a histone-specific acetyltransferase activity" . Mol. Cell. Biol . 19 (11): 7697–704. doi :10.1128/mcb.19.11.7697 . PMC 84812 PMID 10523658 .
Further reading
Jang KL, Collins MK, Latchman DS (1992). "The human immunodeficiency virus tat protein increases the transcription of human Alu repeated sequences by increasing the activity of the cellular transcription factor TFIIIC". J. Acquir. Immune Defic. Syndr . 5 (11): 1142–7. PMID 1403646 . Kovelman R, Roeder RG (1992). "Purification and characterization of two forms of human transcription factor IIIC" . J. Biol. Chem . 267 (34): 24446–56. doi :10.1016/S0021-9258(18)35787-9 PMID 1447193 . Wang Z, Roeder RG (1998). "DNA topoisomerase I and PC4 can interact with human TFIIIC to promote both accurate termination and transcription reinitiation by RNA polymerase III" . Mol. Cell . 1 (5): 749–57. doi :10.1016/S1097-2765(00)80074-X PMID 9660958 . Loftus BJ, Kim UJ, Sneddon VP, Kalush F, Brandon R, Fuhrmann J, Mason T, Crosby ML, Barnstead M, Cronin L, Deslattes Mays A, Cao Y, Xu RX, Kang HL, Mitchell S, Eichler EE, Harris PC, Venter JC, Adams MD (1999). "Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q". Genomics . 60 (3): 295–308. doi :10.1006/geno.1999.5927 . PMID 10493829 . Hsieh YJ, Kundu TK, Wang Z, Kovelman R, Roeder RG (1999). "The TFIIIC90 subunit of TFIIIC interacts with multiple components of the RNA polymerase III machinery and contains a histone-specific acetyltransferase activity" . Mol. Cell. Biol . 19 (11): 7697–704. doi :10.1128/mcb.19.11.7697 . PMC 84812 PMID 10523658 . Meissner W, Thomae R, Seifart KH (2002). "The activity of transcription factor IIIC1 is impaired during differentiation of F9 cells" . J. Biol. Chem . 277 (9): 7148–56. doi :10.1074/jbc.M108721200 PMID 11741993 . Zhan Y, Hegde R, Srinivasula SM, Fernandes-Alnemri T, Alnemri ES (2002). "Death effector domain-containing proteins DEDD and FLAME-3 form nuclear complexes with the TFIIIC102 subunit of human transcription factor IIIC" . Cell Death Differ . 9 (4): 439–47. doi :10.1038/sj.cdd.4401038 PMID 11965497 . Weser S, Riemann J, Seifart KH, Meissner W (2003). "Assembly and isolation of intermediate steps of transcription complexes formed on the human 5S rRNA gene" . Nucleic Acids Res . 31 (9): 2408–16. doi :10.1093/nar/gkg345 . PMC 154231 PMID 12711686 . Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins" . Proc. Natl. Acad. Sci. U.S.A . 101 (33): 12130–5. Bibcode :2004PNAS..10112130B . doi :10.1073/pnas.0404720101 PMC 514446 PMID 15302935 . Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol . 24 (10): 1285–92. doi :10.1038/nbt1240 . PMID 16964243 . S2CID 14294292 . Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks" . Cell . 127 (3): 635–48. doi :10.1016/j.cell.2006.09.026 PMID 17081983 . S2CID 7827573 . Dumay-Odelot H, Marck C, Durrieu-Gaillard S, Lefebvre O, Jourdain S, Prochazkova M, Pflieger A, Teichmann M (2007). "Identification, molecular cloning, and characterization of the sixth subunit of human transcription factor TFIIIC" . J. Biol. Chem . 282 (23): 17179–89. doi :10.1074/jbc.M611542200 PMID 17409385 .
External links
This article incorporates text from the United States National Library of Medicine , which is in the public domain .
(1) Basic domains
(1.1) Basic leucine zipper (bZIP )(1.2) Basic helix-loop-helix (bHLH )
Group A Group B Group CPAS Group D Group E Group F
(1.3) bHLH-ZIP (1.4) NF-1 (1.5) RF-X (1.6) Basic helix-span-helix (bHSH)
(2) Zinc finger DNA-binding domains
(2.1) Nuclear receptor (Cys4 )
subfamily 1 subfamily 2 subfamily 3 subfamily 4 subfamily 5 subfamily 6 subfamily 0
(2.2) Other Cys4 (2.3) Cys2 His2 (2.4) Cys6 (2.5) Alternating composition (2.6) WRKY
(4) β-Scaffold factors with minor groove contacts
(0) Other transcription factors
