Dorn (German for thorn) is a German/Austrian and Dutch/Flemish surname.

• Angela Dorn-Rancke, née Dorn, German politician
• August T. Dorn (1849–1923), American politician
• David Dorn (1942–2020), African-American retired police chief murdered after interrupting a burglary
• Dieter Dorn (born 1935), German theatre director
• Dolores Dorn (1934–2019), American film actor
• Edward John Dorn (1854–1937), United States naval officer and Governor of Guam
• Ed Dorn (1929–1999), American poet
• Friedrich Ernst Dorn (1848–1916), German physicist
• Francis E. Dorn (1911–1987), member of the United States House of Representatives
• George W. Dorn (1836–1891), President of the Chico Board of Trustees in 1872
• Gerhard Dorn (c. 1530–1584), Belgian philosopher, translator, alchemist, physician and bibliophile
• Heinrich Dorn (1804–1892), German conductor and composer
• Ivan Dorn (born 1988), Ukrainian singer, DJ, TV presenter and producer
• Jennifer Dunbar Dorn, English writer and filmmaker
• Joel Dorn (1942–2007), music producer
• Johannes Albrecht Bernhard Dorn (1805–1881), German orientalist
• Ludwik Dorn (1954–2022), Polish politician
• Luke Dorn (born 1982), rugby player
• Michael Dorn (born 1952), American actor
• Myles Dorn (born 1998), American football player
• Robert C. Dorn, New York politician
• Roosevelt F. Dorn (born 1935), mayor
• Rüdiger Dorn (born 1969), game designer
• Thea Dorn (born 1970), German writer
• Walter Dorn (born 1961), scientist, educator, author and researcher
• Willian Dorn (born 1994), Brazilian futsal player
• William Jennings Bryan Dorn (1916–2005), American politician
• Wulf Dorn (born 1969), German novelist

• Eliot Dorn, on the American crime drama series and soap opera The Edge of Night
• Rogal Dorn, one of the twenty primarchs and leader of the Imperial Fists in tabletop game Warhammer 40,000
• Roger Dorn (played by Corbin Bernsen), in the films Major League (1989), Major League II (1994) and Major League: Back to the Minors (1998)
• Chris Dorn and son Kurt Dorn, wheat farmers in Zane Grey's 1919 novel The Desert of Wheat

• Van Dorn (disambiguation), which includes a list of people with the surname Van Dorn or van Dorne