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Clove

Clove
Scientific classification Edit this classification
Kingdom: Plantae
Clade: Tracheophytes
Clade: Angiosperms
Clade: Eudicots
Clade: Rosids
Order: Myrtales
Family: Myrtaceae
Genus: Syzygium
Species:
S. aromaticum
Binomial name
Syzygium aromaticum
Synonyms[1]
  • Caryophyllus aromaticus L.
  • Eugenia aromatica (L.) Baill.
  • Eugenia caryophyllata Thunb.
  • Eugenia caryophyllus (Spreng.) Bullock & S.G.Harrison
  • Jambosa caryophyllus (Thunb.) Nied.

Cloves are the aromatic flower buds of a tree in the family Myrtaceae, Syzygium aromaticum (/sɪˈzɪəm ˌærəˈmætɪkəm/).[2][3] They are native to the Maluku Islands, or Moluccas, in Indonesia, and are commonly used as a spice, flavoring, or fragrance in consumer products, such as toothpaste, soaps, or cosmetics.[4][5] Cloves are available throughout the year owing to different harvest seasons across various countries.[6]

Etymology

The word clove, first used in English in the 15th century, derives via Middle English clow of gilofer,[7] Anglo-French clowes de gilofre and Old French clou de girofle, from the Latin word clavus "nail".[8][9] The related English word gillyflower, originally meaning "clove", derives[10] via said Old French girofle and Latin caryophyllon, from the Greek karyophyllon "clove", literally "nut leaf".[11][7]

Description

The clove tree is an evergreen that grows up to 8–12 metres (26–39 ft) tall, with large leaves and crimson flowers grouped in terminal clusters. The flower buds initially have a pale hue, gradually turn green, then transition to a bright red when ready for harvest. Cloves are harvested at 1.5–2 centimetres (5834 in) long, and consist of a long calyx that terminates in four spreading sepals, and four unopened petals that form a small central ball.

Clove stalks are slender stems of the inflorescence axis that show opposite decussate branching. Externally, they are brownish, rough, and irregularly wrinkled longitudinally with short fracture and dry, woody texture. Mother cloves (anthophylli) are the ripe fruits of cloves that are ovoid, brown berries, unilocular and one-seeded. Blown cloves are expanded flowers from which both corollae and stamens have been detached. Exhausted cloves have most or all the oil removed by distillation. They yield no oil and are darker in color.[citation needed]

Uses

Dried cloves
Clove tree flowerbuds

Cloves are used in the cuisine of Asian, African, Mediterranean, and the Near and Middle East countries, lending flavor to meats (such as baked ham), curries, and marinades, as well as fruit (such as apples, pears, and rhubarb). Cloves may be used to give aromatic and flavor qualities to hot beverages, often combined with other ingredients such as lemon and sugar. They are a common element in spice blends (as part of the Malay rempah empat beradik –"four sibling spices"– besides cinnamon, cardamom and star anise for example[12]), including pumpkin pie spice and speculaas spices.

In Mexican cuisine, cloves are best known as clavos de olor, and often accompany cumin and cinnamon.[13] They are also used in Peruvian cuisine, in a wide variety of dishes such as carapulcra and arroz con leche.

A major component of clove's taste is imparted by the chemical eugenol,[14] and the quantity of the spice required is typically small. It pairs well with cinnamon, allspice, vanilla, red wine, basil, onion, citrus peel, star anise, and peppercorns.

Non-culinary uses

It is often added to betel quids to enhance aroma while chewing.[15] The spice is used in a type of cigarette called kretek in Indonesia.[1] Clove cigarettes were smoked throughout Europe, Asia, and the United States. Clove cigarettes are currently classified in the United States as cigars,[16] the result of a ban on flavored cigarettes in September 2009.[17]

Clove essential oil may be used to inhibit mold growth on various types of foods.[18] In addition to these non-culinary uses of clove, it can be used to protect wood in a system for cultural heritage conservation, and showed the efficacy of clove essential oil to be higher than a boron-based wood preservative.[19] Cloves can be used to make a fragrant pomander when combined with an orange. When given as a gift in Victorian England, such a pomander indicated warmth of feeling.

Cloves drying in sun

Potential medicinal uses and adverse effects

The use of clove for any medicinal purpose has not been approved by the US Food and Drug Administration, and its use may cause adverse effects if taken orally by people with liver disease, blood clotting and immune system disorders, or food allergies.[5]

Cloves are used in traditional medicine as an essential oil, which is used as an anodyne (analgesic) mainly for dental emergencies and other disorders.[20] There is evidence that clove oil containing eugenol is effective for toothache pain and other types of pain,[5][21][22] and one review reported the efficacy of eugenol combined with zinc oxide as an analgesic for alveolar osteitis.[23] Clove essential oil may prevent the growth of Enterococcus faecalis bacteria which is often present in a root canal treatment failure.[24]

Studies to determine its effectiveness for fever reduction, as a mosquito repellent, and to prevent premature ejaculation have been inconclusive.[5][21] It remains unproven whether blood sugar levels are reduced by cloves or clove oil.[21] The essential oil may be used in aromatherapy.[5]

History

Austronesian proto-historic and historic maritime trade network in the Indian Ocean[25]

Until the colonial era, cloves only grew on a few islands in the Moluccas (historically called the Spice Islands), including Bacan, Makian, Moti, Ternate, and Tidore.[26]

Cloves were first traded by the Austronesian peoples in the Austronesian maritime trade network (which began around 1500 BC, later becoming the Maritime Silk Road and part of the Spice Trade).[citation needed] The first notable example of modern clove farming developed on the east coast of Madagascar, and is cultivated in three separate ways, a monoculture, agricultural parklands, and agroforestry systems.[27]

Archaeologist Giorgio Buccellati found cloves in Terqa, Syria, in a burned-down house which was dated to 1720 BC during the kingdom of Khana. This was the first evidence of cloves being used in the west before Roman times. The discovery was first reported in 1978.[28][29][30] They reached Rome by the first century AD.[31][32][33][34]

Other archeological finds of cloves include: At the Batujaya site a single clove was found in a waterlogged layer dating to between the 100s BC to 200s BC corresponding to the Buni culture phase of this site.[35] A study at the site of Óc Eo in the Mekong Delta of Vietnam found starch grains of cloves on stone implements used in food processing. This site was occupied from the first to eighth century BC, and was a trading center for the kingdom of Funnan.[36] Two cloves were found during archaeological excavations at the Sri Lankan city of Mantai dated to around 900–1100 AD.[37][38]

Cloves are mentioned in the Ramayana.[39] Cloves are also mentioned in the Charaka Samhita.[35][40] One of the earliest examples of literary evidence of cloves in China is from the book the Han Guan Yi (Etiquettes of the Officialdom of the Han Dynasty, dating to around 200 BC). The book states a rule that ministers should suck cloves to sweeten their breath before speaking to the emperor.[citation needed] From Chinese records during the Song Dynasty (960 to 1279 AD) cloves were primarily imported by private ventures, called Merchant Shipping Offices, who bought goods from middlemen in the Austronesian polities of Java, Srivijaya, Champa, and Butuan. During the Yuan dynasty (1271 to 1368 AD) Chinese merchants began sending ships directly to the Moluccas to trade for cloves, and other spices.[36][41]

In the Western Classical literature cloves are mentioned by Pliny the Elders' Natural History.[citation needed] Dioscorides mentions cloves in his book De materia medica.[citation needed] The Liber Pontifcalis records an endowment made by Passinopolis under Pope Sylvester I. This endowment included an Egyptian estate, its annual revenues, 150 libra (around 50 kg or 108 lb) of cloves, and other amounts of spices and papyrus.[42] Cosmas Indicopleustis in his book Topographia Christiana outlined his travels to Sri Lanka, and recounted that the Indians said that cloves, among other products, came in from unspecified places along sea trade routes.[35][citation needed]

Cloves were also present in records in China, Sri Lanka, Southern India, Persia, and Oman by around the third century to second century BC.[31][32][33] These mentions of "cloves" reported in China, South Asia, and the Middle East come from before the establishment of Southeast Asian maritime trade. But all of these are misidentifications that referred to other plants (like cassia buds, cinnamon, or nutmeg); or are imports from Maritime Southeast Asia mistakenly identified as being natively produced in these regions.[41]

Archaeologists recovered the earliest known example of macro-botanical cloves in northwest Europe from the wreck of the Danish-Norwegian flagship, Gribshunden. The ship sank near Ronneby, Sweden in June 1495 while King Hans was sailing to political summit at Kalmar, Sweden. Exotic luxuries including cloves, ginger, peppercorns, and saffron would have impressed the noblemen and high church officials at the summit.[43]

Cloves have been documented in the burial practices of Europeans from the late middle ages into the early modern period. During renovations on the Grote Kerk of Breda a tomb was rediscovered that was used between 1475 and 1526 AD by eight members of the house of Nassau. These burials had to be moved, but before being re-interred these burials were studied for botanical remains. The burial of Cimberga van Baden contained pollen from cloves. The Dutch Physician Pieter Van Foreest wrote down multiple recipes for embalming some of which included cloves. One of these recipes he wrote down was that used by his fellow physicians Spierinck and Goethals.[44] An embalming jar associated with Vittoria della Rovere also contained clove pollen. This probably came from her ingestion of clove oil as a medicine in her final days.[45][46][47] When burials needed to be moved from the church of Saint Germain in Flers, France they were also studied for botanical remains. The body and coffin of Philippe René de la Motte Ango, count of Flers who was buried in 1737 AD contained whole cloves.[48]

During the colonial era, cloves were traded like oil, with an enforced limit on exportation.[49] As the Dutch East India Company consolidated its control of the spice trade in the 17th century, they sought to gain a monopoly in cloves as they had in nutmeg. However, "unlike nutmeg and mace, which were limited to the minute Bandas, clove trees grew all over the Moluccas, and the trade in cloves was beyond the limited policing powers of the corporation".[50] One clove tree named Afo that experts believe is the oldest in the world on Ternate may be 350–400 years old.[49] Tourists are told that seedlings from this very tree were stolen by a Frenchman named Pierre Poivre in 1770, transferred to the Isle de France (Mauritius), and then later to Zanzibar, which was once the world's largest producer of cloves.[49]

Current leaders in clove production are Indonesia, Madagascar, Tanzania, Sri Lanka, and Comoros.[51] Indonesia is the largest clove producer, but only about 10-15% of its cloves production is exported, and domestic shortfalls must sometimes be filled with imports from Madagascar.[51] The modern province of Maluku remains the largest source of cloves in Indonesia with around 15% of national production, although provinces comprising the island of Sulawesi produced over 40% collectively.[52]

Phytochemicals

The compound eugenol is responsible for most of the characteristic aroma of cloves.

Eugenol comprises 72–90% of the essential oil extracted from cloves, and is the compound most responsible for clove aroma.[14][53] Complete extraction occurs at 80 minutes in pressurized water at 125 °C (257 °F).[54] Ultrasound-assisted and microwave-assisted extraction methods provide more rapid extraction rates with lower energy costs.[55]

Other phytochemicals of clove oil include acetyl eugenol, beta-caryophyllene, vanillin, crategolic acid, tannins, such as bicornin,[14][56] gallotannic acid, methyl salicylate, the flavonoids eugenin, kaempferol, rhamnetin, and eugenitin, triterpenoids such as oleanolic acid, stigmasterol, and campesterol and several sesquiterpenes.[5] Although eugenol has not been classified for its potential toxicity,[53] it was shown to be toxic to test organisms in concentrations of 50, 75, and 100 mg per liter.[57]

See also

References

  1. ^ a b "Syzygium aromaticum (L.) Merr. & L.M.Perry". Germplasm Resources Information Network. Agricultural Research Service, United States Department of Agriculture. Retrieved June 9, 2011.
  2. ^ "syzygium". Oxford English Dictionary (Online ed.). Oxford University Press. (Subscription or participating institution membership required.)
  3. ^ "aqua aromatica". Merriam-Webster.com Dictionary. Merriam-Webster.
  4. ^ "Syzygium aromaticum (L.) Merr. and L.M. Perry". Kew Science, Plants of the World Online. 2021. Retrieved 28 February 2021.
  5. ^ a b c d e f "Clove". Drugs.com. 5 March 2018. Retrieved 9 November 2018.
  6. ^ Yun, Wonjung (13 August 2018). "Tight Stocks of Quality Cloves Lead to a Price Surge". Tridge. Archived from the original on 14 August 2018. Retrieved 13 August 2018.
  7. ^ a b Uchibayashi, M. (2001). "[Etymology of clove]". Yakushigaku Zasshi. 36 (2): 167–170. ISSN 0285-2314. PMID 11971288.
  8. ^ Harper, Douglas. "clove". Online Etymology Dictionary.
  9. ^ clavus. Charlton T. Lewis and Charles Short. A Latin Dictionary on Perseus Project.
  10. ^ Harper, Douglas. "gillyflower". Online Etymology Dictionary.
  11. ^ καρυόφυλλον. Liddell, Henry George; Scott, Robert; A Greek–English Lexicon at the Perseus Project
  12. ^ Hariati Azizan (Aug 2, 2015). "A spicy blend of tradition". Star2. The Star. p. 9.
  13. ^ Dorenburg, Andrew and Page, Karen. The New American Chef: Cooking with the Best Flavors and Techniques from Around the World, John Wiley and Sons Inc., 2003
  14. ^ a b c Kamatou, G. P.; Vermaak, I.; Viljoen, A. M. (2012). "Eugenol--from the remote Maluku Islands to the international market place: a review of a remarkable and versatile molecule". Molecules. 17 (6): 6953–81. doi:10.3390/molecules17066953. PMC 6268661. PMID 22728369.
  15. ^ Rooney, Dawn F. (1993). Betel Chewing Traditions in South-East Asia. Kuala Lumpur: Oxford University Press. p. 26. ISBN 0-19-588620-8.
  16. ^ "Flavored Tobacco". FDA. Retrieved September 7, 2012.
  17. ^ "The Tobacco Control Act's Ban of Clove Cigarettes and the WTO: A Detailed Analysis". Congressional Research Service Reports. 17 September 2012. Retrieved 2022-05-12.
  18. ^ Ju, Jian; Xu, Xiaomiao; Xie, Yunfei; Guo, Yahui; Cheng, Yuliang; Qian, He; Yao, Weirong (2018). "Inhibitory effects of cinnamon and clove essential oils on mold growth on baked foods". Food Chemistry. 240: 850–855. doi:10.1016/j.foodchem.2017.07.120. PMID 28946351.
  19. ^ Pop, Dana-Mihaela; Timar, Maria Cristina; Varodi, Anca Maria; Beldean, Emanuela Carmen (December 2021). "An evaluation of clove (Eugenia caryophyllata) essential oil as a potential alternative antifungal wood protection system for cultural heritage conservation". Maderas. Ciencia y tecnología. 24. doi:10.4067/S0718-221X2022000100411. ISSN 0718-221X. S2CID 245952586.
  20. ^ Balch, Phyllis and Balch, James. Prescription for Nutritional Healing, 3rd ed., Avery Publishing, 2000, p. 94
  21. ^ a b c "Clove". MedlinePlus, U.S. National Library of Medicine and National Institutes of Health. 2014. Retrieved August 18, 2014.
  22. ^ "Eugenol - COLCORONA Clinical Trial". www.colcorona.net. Retrieved 2022-12-12.
  23. ^ Taberner-Vallverdú, M.; Nazir, M.; Sanchez-Garces, M. Á.; Gay-Escoda, C. (2015). "Efficacy of different methods used for dry socket management: A systematic review". Medicina Oral Patología Oral y Cirugia Bucal. 20 (5): e633–e639. doi:10.4317/medoral.20589. PMC 4598935. PMID 26116842.
  24. ^ Sarahfin Aslan; Masriadi; Nur Rahmah Hasanuddin; Andi Tenri Biba Mallombasang; Nur Azizah a.r (2022). "Effectiveness of Mixed Clove Flower Extract (Syzygium Aromaticum) And Sweet Wood (Cinnamon Burmanni) on the Growth of Enterococcus Faecalis". Indian Journal of Forensic Medicine & Toxicology. 16 (1): 1089–1094. doi:10.37506/ijfmt.v16i1.17639. S2CID 245045753.
  25. ^ Manguin, Pierre-Yves (2016). "Austronesian Shipping in the Indian Ocean: From Outrigger Boats to Trading Ships". In Campbell, Gwyn (ed.). Early Exchange between Africa and the Wider Indian Ocean World. Palgrave Macmillan. pp. 51–76. ISBN 978-3-319-33822-4.
  26. ^ Turner, Jack (2004). Spice: The History of a Temptation. Vintage Books. pp. xxvii–xxviii. ISBN 978-0-375-70705-6.
  27. ^ Arimalala, Natacha; Penot, Eric; Michels, Thierry; Rakotoarimanana, Vonjison; Michel, Isabelle; Ravaomanalina, Harisoa; Roger, Edmond; Jahiel, Michel; Leong Pock Tsy, Jean-Michel; Danthu, Pascal (August 2019). "Clove based cropping systems on the east coast of Madagascar: how history leaves its mark on the landscape". Agroforestry Systems. 93 (4): 1577–1592. Bibcode:2019AgrSy..93.1577A. doi:10.1007/s10457-018-0268-9. ISSN 0167-4366. S2CID 49583653.
  28. ^ Buccellati, G., M. Kelly-Buccellati, The Terqa Archaeological Project: First Preliminary Report., Les Annales Archeologiques Arabes Syriennes 27–28, 1977–1978, 71–96.
  29. ^ Buccellati, G., M. Kelly-Buccellati, Terqa: The First Eight Seasons, Les Annales Archeologiques Arabes Syriennes 33(2), 1983, 47–67.
  30. ^ Terqa – A Narrative. terqa.org.
  31. ^ a b Mahdi, Waruno (2003). "Linguistic and philological data towards a chronology of Austronesian activity in India and Sri Lanka". In Blench, Roger; Spriggs, Matthew (eds.). Archaeology and Language IV: Language Change and Cultural Transformation. Routledge. pp. 160–240. ISBN 978-1-134-81624-8.
  32. ^ a b Ardika, I Wayan (2021). "Bali in the Global Contacts and the Rise of Complex Society". In Prasetyo, Bagyo; Nastiti, Titi Surti; Simanjuntak, Truman (eds.). Austronesian Diaspora: A New Perspective. UGM Press. p. 196. ISBN 978-602-386-202-3.
  33. ^ a b "Cloves". Silk Routes. The University of Iowa. Retrieved 24 January 2022.
  34. ^ Smith, Monica (2019). "The Terqa Cloves and the Archaeology of Aroma" (PDF). In Valentini, Stefano; Guarducci, Guido; Buccellati, Giorgio; Kelly-Buccellati, Marilyn (eds.). Between Syria and the Highlands: Studies in Honor of Giorgio Buccellati & Marilyn Kelly-Buccellati. Rome: Arbor Sapientiae Editore. pp. 373–377. ISBN 978-8831341011.
  35. ^ a b c Cobb, Matthew Adam (2024-07-17), "Spices in the Ancient World", Oxford Research Encyclopedia of Food Studies, Oxford University Press, doi:10.1093/acrefore/9780197762530.013.43, ISBN 978-0-19-776253-0, retrieved 2024-07-26
  36. ^ a b Wang, Weiwei; Nguyen, Khanh Trung Kien; Zhao, Chunguang; Hung, Hsiao-chun (2023-07-21). "Earliest curry in Southeast Asia and the global spice trade 2000 years ago". Science Advances. 9 (29): eadh5517. Bibcode:2023SciA....9H5517W. doi:10.1126/sciadv.adh5517. ISSN 2375-2548. PMC 10361603. PMID 37478176.
  37. ^ Kingwell-Banham, Eleanor (15 January 2019). "World's oldest clove? Here's what our find in Sri Lanka says about the early spice trade". The Conversation.
  38. ^ Kingwell-Banham, Eleanor; Bohingamuwa, Wijerathne; Perera, Nimal; Adikari, Gamini; Crowther, Alison; Fuller, Dorian Q; Boivin, Nicole (December 2018). "Spice and rice: pepper, cloves and everyday cereal foods at the ancient port of Mantai, Sri Lanka". Antiquity. 92 (366): 1552–1570. doi:10.15184/aqy.2018.168. ISSN 0003-598X.
  39. ^ Shastri, Hariprasad (1952). The Ramayana of Valmiki. Bristol: Burleigh Press. pp. 354, Book 2 Chapter 91. ISBN 9789333119597.
  40. ^ https://www.wisdomlib.org/hinduism/essay/charaka-samhita-and-sushruta-samhita/d/doc1147016.html. Charaka Samhita and Sushruta Samhita. Translated by Sharma, Nayana. 2015. pp. Chapter 6, § Personal Hygiene. {{cite book}}: |chapter-url= missing title (help)
  41. ^ a b Ptak, Roderich (January 1993). "China and the Trade in Cloves, Circa 960–1435". Journal of the American Oriental Society. 113 (1): 1–13. doi:10.2307/604192. JSTOR 604192.
  42. ^ The Book of the Popes (Liber Pontificalis): To the Pontificate of Gregory I (PDF). Translated by Loomis, Louise Ropes. New York: Columbia University Press. 1916. pp. 56–57.
  43. ^ Larsson, Mikael; Foley, Brendan (2023-01-26). "The king's spice cabinet–Plant remains from Gribshunden, a 15th century royal shipwreck in the Baltic Sea". PLOS ONE. 18 (1): e0281010. Bibcode:2023PLoSO..1881010L. doi:10.1371/journal.pone.0281010. ISSN 1932-6203. PMC 9879437. PMID 36701280.
  44. ^ Vermeeren, Caroline; van Haaster, Henk (June 2002). "The embalming of the ancestors of the Dutch royal family". Vegetation History and Archaeobotany. 11 (1–2): 121–126. Bibcode:2002VegHA..11..121V. doi:10.1007/s003340200013. ISSN 0939-6314.
  45. ^ Schrage, Scott. "In case you missed it: Study reveals deathbed detail of 17th-century duchess". University of Nebraska Lincoln Newsroom. Archived from the original on 9 October 2021. Retrieved 26 July 2024.
  46. ^ Wei-Haas, Maya (21 September 2018). "Noble's Embalming Jar Reveals Traces of 17th-Century Medicine". National Geographic. Retrieved 26 July 2024.
  47. ^ Reinhard, Karl; Lynch, Kelsey B.; Larsen, Annie; Adams, Braymond; Higley, Leon; do Amaral, Marina Milanello; Russ, Julia; Zhou, You; Lippi, Donatella; Morrow, Johnica J.; Piombino-Mascali, Dario (October 2018). "Pollen evidence of medicine from an embalming jar associated with Vittoria della Rovere, Florence, Italy". Journal of Archaeological Science: Reports. 21: 238–242. Bibcode:2018JArSR..21..238R. doi:10.1016/j.jasrep.2018.06.039.
  48. ^ Corbineau, Rémi; Ruas, Marie-Pierre; Barbier-Pain, Delphine; Fornaciari, Gino; Dupont, Hélène; Colleter, Rozenn (January 2018). "Plants and aromatics for embalming in Late Middle Ages and modern period: a synthesis of written sources and archaeobotanical data (France, Italy)". Vegetation History and Archaeobotany. 27 (1): 151–164. Bibcode:2018VegHA..27..151C. doi:10.1007/s00334-017-0620-4. ISSN 0939-6314.
  49. ^ a b c Worrall, Simon (23 June 2012). "The world's oldest clove tree". BBC News Magazine. Retrieved June 24, 2012.
  50. ^ Krondl, Michael. The Taste of Conquest: The Rise and Fall of the Three Great Cities of Spice. New York: Ballantine Books, 2007.
  51. ^ a b Pratama, Adnan Putra; Darwanto, Dwidjono Hadi; Masyhuri, Masyhuri (2020-02-01). "Indonesian Clove Competitiveness and Competitor Countries in International Market". Economics Development Analysis Journal. 9 (1): 39–54. doi:10.15294/edaj.v9i1.38075. ISSN 2252-6560. S2CID 219679994.
  52. ^ "OUTLOOK KOMODITAS PERKEBUNAN PUSAT DATA DAN SISTEM INFORMASI PERTANIAN SEKRETARIAT JENDERAL - KEMENTERIAN PERTANIAN TAHUN 2022 CENGKEH" (PDF) (in Indonesian). Ministry of Agriculture. Retrieved 15 October 2024.
  53. ^ a b "Eugenol". PubChem, US National Library of Medicine. 2 November 2019. Retrieved 10 November 2019.
  54. ^ Rovio, S.; Hartonen, K.; Holm, Y.; Hiltunen, R.; Riekkola, M.-L. (7 February 2000). "Extraction of clove using pressurized hot water". Flavour and Fragrance Journal. 14 (6): 399–404. doi:10.1002/(SICI)1099-1026(199911/12)14:6<399::AID-FFJ851>3.0.CO;2-A.
  55. ^ Khalil, A.A.; ur Rahman, U.; Khan, M.R.; Sahar, A.; Mehmood, T.; Khan, M. (2017). "Essential oil eugenol: sources, extraction techniques and nutraceutical perspectives". RSC Advances. 7 (52): 32669–32681. Bibcode:2017RSCAd...732669K. doi:10.1039/C7RA04803C.
  56. ^ Li-Ming Bao, Eerdunbayaer; Nozaki, Akiko; Takahashi, Eizo; Okamoto, Keinosuke; Ito, Hideyuki; Hatano, Tsutomu (2012). "Hydrolysable tannins isolated from Syzygium aromaticum: Structure of a new c-glucosidic ellagitannin and spectral features of tannins with a tergalloyl group". Heterocycles. 85 (2): 365–381. doi:10.3987/COM-11-12392.
  57. ^ Gueretz, Juliano Santos; Somensi, Cleder Alexandre; Martins, Maurício Laterça; Souza, Antonio Pereira de (2017-12-07). "Evaluation of eugenol toxicity in bioassays with test-organisms". Ciência Rural. 47 (12). doi:10.1590/0103-8478cr20170194. ISSN 1678-4596.