Cilazapril

Names
Preferred IUPAC name (1S,9S)-9-{[(2S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-10-oxooctahydro-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid
Identifiers
CAS Number	88768-40-5 N
3D model (JSmol)	Interactive image
ChEBI	CHEBI:3698
ChEMBL	ChEMBL515606 N
ChemSpider	50831 N
DrugBank	DB01340 Y
ECHA InfoCard	100.168.764
IUPHAR/BPS	6459
KEGG	D07699 Y
PubChem CID	56330 40467985 (1R,9S)-(2S)-butylamino isomer
UNII	8Q9454114Q N
CompTox Dashboard (EPA)	DTXSID1048629
InChI InChI=1S/C22H31N3O5/c1-2-30-22(29)18(13-12-16-8-4-3-5-9-16)23-17-10-6-14-24-15-7-11-19(21(27)28)25(24)20(17)26/h3-5,8-9,17-19,23H,2,6-7,10-15H2,1H3,(H,27,28) N Key: HHHKFGXWKKUNCY-UHFFFAOYSA-N N
SMILES CCOC(=O)C(CCc1ccccc1)NC1CCCN2CCCC(N2C1=O)C(O)=O
Properties
Chemical formula	C22H31N3O5
Molar mass	417.506 g·mol−1
log P	2.212
Acidity (pKa)	2.285
Basicity (pKb)	11.712
Pharmacology
ATC code	C09AA08 (WHO)
Routes of administration	Oral
Legal status	UK: POM (Prescription only)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

Cilazapril is an angiotensin-converting enzyme inhibitor (ACE inhibitor) used for the treatment of hypertension and congestive heart failure.^[1][2]

It was patented in 1982 and approved for medical use in 1990.^[3]

Of the eight possible stereoisomers, only the all-(S)-form is medically viable.^{[citation needed]}

It is branded as Dynorm, Inhibace, Vascace and many other names in various countries. None of these are available in the United States as of May 2010.^[4]