Rene-Guy Charles Okala (19 October 1910 – 16 September 1973) was a Cameroonian politician. Born in Bilomo in the Centre Region in 1910, he attended a Catholic primary school in Yaoundé.^[1]

Following World War II, Okala was elected to the local assembly and became a member of the French Senate in 1947, serving until 1955.^[2] He was minister of justice from xxx to xxx.^[3] In 1959 he established the Socialist Party of Cameroon (PSC), which contested the 1960 elections as part of the Group of Cameroonian Progressives. In 1960 he was appointed independent Cameroon's first Foreign Minister.

Okala was sacked in 1961 and arrested in June 1962, then tried for and convicted of conspiracy. He was released from prison in 1965 as part of a deal that involved the dissolution of the PSC, then joined the Cameroonian Union and its successor the Cameroon National Union.^[1] He was appointed a roving ambassador by President Ahmadou Ahidjo in 1968, before falling out of favour.^[1] He died in Paris in 1973.^[2]