The Centers for Disease Control and Prevention is the national public health agency of the United States.

CDC may also refer to:

• Coalition to Diversify Computing, a joint organization of the Association for Computing Machinery (ACM) and the Computing Research Association (CRA)

• Caisse des dépôts et consignations ("Deposits and Consignments Fund"), a financial institution owned by the French government
• Cameroon Development Corporation, an agribusiness company located in Limbe, Cameroon
• CDC Group, formerly the Commonwealth Development Corporation and Colonial Development Corporation, a British development organisation owned by the UK Government
• Central Depository Company, a Pakistani central securities depository company
• ComfortDelGro Australia, a major Australian operator of buses formerly named ComfortDelGro Cabcharge
• Control Data Corporation, former supercomputer company
• Construction Data Company, also known as CDC News and CDC Publishing, a commercial construction reporting service
• Loong Air, by ICAO code

• Africa Centres for Disease Control
• Canadian Dairy Commission
• Chichester District Council, local authority in West Sussex, England
• Chinese Center for Disease Control and Prevention
• Civil Defence Corps, UK, 1949–1968
• Colonial Defence Committee, a body advising on the military defence of the British Empire, 1885–1908
• Community Development Council, Singapore
• Community of Democratic Choice, of Eastern European countries
• Hong Kong Curriculum Development Council, Hong Kong
• Korea Centers for Disease Control and Prevention, a South Korean agency
• Taiwan Centers for Disease Control

• Certified Development Company, a U.S. Small Business Administration program designed to provide financing for the purchase of fixed assets
• Community development corporation, any non-profit organization that promotes and supports a community
• Commission for Developing Countries, a Commission of the International Mathematical Union

• California Democratic Council, US
• Coalition for Democratic Change, a Liberian political alliance
• Congress for Democratic Change, a Liberian political party
• Democratic Convergence of Catalonia (Catalan: Convergència Democràtica de Catalunya), a political party in Catalonia, Spain 1974–2016

• Cricket Discipline Commission (of the England and Wales Cricket Board)

• Cult of the Dead Cow (cDc), a computer hacker and DIY media organization

• Cedar City Regional Airport, by IATA code
• Center Day Camp, North Windham, Maine, U.S.
• Communicable Disease Centre, former hospital in Novena, Singapore

• Cell-division cycle in biology
  • cdc20
  • cdc25
  • Cdc42, cell-division cycle protein
• Cholesterol-dependent cytolysin, exotoxins secreted by bacteria
• Complement-dependent cytotoxicity
• Conventional dendritic cell, cDC
• Cross dehydrogenative coupling

• Carbide-derived carbon
• Change data capture, to track changed data
• Clock domain crossing of a signal
• Communications daughter card for notebook computers
• Connected Device Configuration, of required Java ME features
• USB communications device class

• CDC?, a children's book by William Steig
• Chef de cuisine
• Combat Direction Center of an aircraft carrier
• Continuous Discharge Certificate, seafarer's identity document
• Cul de canard, duck feathers used in fly fishing

• Africa CDC (Centres for Disease Control and Prevention)
• C.DC., the Swiss botany author abbreviation of Anne Casimir de Candolle