BBO may stand for:

• Barium boron oxide, another name of barium borate
• Big Bang Observer, planned space gravitational wave observatory
• IATA code for Berbera Airport
• "BBO (Bad Bitches Only)", a song by Migos from the album Culture II
• Beta barium borate (β-BaB₂O₄) crystal
• Bundesbahn Österreich, a former name for the Austrian Federal Railways
• Bureau Bijzondere Opdrachten, a WWII Dutch secret service
• Bridge Base Online, for the game of bridge
• British Ballet Organization
• BBO, the ICAO code for Flybaboo