Singles
1990 Grand Prix de Tennis de Lyon
Final
Champion	Marc Rosset
Runner-up	Mats Wilander
Score	6–3, 6–2
Details
Draw	32
Seeds	8
Events
Singles Doubles
← 1989 · Grand Prix de Tennis de Lyon · 1991 →

The 1990 Grand Prix de Tennis de Lyon – Singles was an event of the 1990 Grand Prix de Tennis de Lyon men's tennis tournament that was played at the Palais des Sports de Gerland in Lyon, France from 15 October until 22 October 1990. The draw comprised 32 players and eight were seeded. John McEnroe was the defending champion, but did not participate this year. Sixth-seeded Marc Rosset won the singles title, defeating unseeded Mats Wilander, in the final, 6–3, 6–2.^[1]

	Semifinals							Final
	Q	Alexander Mronz	2	6
		Mats Wilander	6	7
									Mats Wilander	3	2
								6	Marc Rosset	6	6
	6	Marc Rosset	6	1	6
		David Pate	4	6	4

	First round							Second round							Quarterfinals							Semifinals
	1	A Krickstein	7	6
	Q	Y Doumbia	6	4				1	A Krickstein	6	6
		C Bergström	6	6					C Bergström	4	3
	LL	C Suk	1	2											1	A Krickstein	4	6	4
	Q	L Jensen	3	6											Q	A Mronz	6	2	6
	WC	É Winogradsky	6	7				WC	É Winogradsky	7	4	4
	Q	A Mronz	3	6	6			Q	A Mronz	6	6	6
	8	J-P Fleurian	6	3	0																	Q	A Mronz	2	6
	3	J Svensson	6	6																			M Wilander	6	7
		T Benhabiles	2	3				3	J Svensson	6	7
		E Masso	7	6					E Masso	4	6
	Q	P Gauthier	6	2											3	J Svensson	6	4	3
		D Pérez	1	6	0											M Wilander	4	6	6
		G Bloom	6	0	6				G Bloom	2	2
		M Wilander	6	3	6				M Wilander	6	6
	5	A Cherkasov	2	6	3

	First round							Second round							Quarterfinals							Semifinals
	6	M Rosset	7	6	7
		M Šrejber	6	7	6			6	M Rosset	6	3	6
		E Jelen	5	6	7				E Jelen	1	6	3
		M Washington	7	0	5										6	M Rosset	7	7
		F Santoro	1	6	3										4	R Agénor	6	5
		R Krishnan	6	4	6				R Krishnan	6	6	5
		B Shelton	7	3	1			4	R Agénor	1	7	7
	4	R Agénor	6	6	6																	6	M Rosset	6	1	6
	7	Y Noah	3	7	6																		D Pate	4	6	4
		K Jones	6	5	3			7	Y Noah	2	4
	WC	G Raoux	3	4					G Muller	6	6
		G Muller	6	6												G Muller	6	6	3
		T Champion	6	6												D Pate	7	4	6
	WC	C Pioline	4	3					T Champion	3	6	3
		D Pate	7	4	7				D Pate	6	3	6
	2	G Forget	6	6	6

• Main draw